A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.
Antimetabolites are drugs that interfere with one or more enzymes or their reactions that are necessary for DNA synthesis. They affect DNA synthesis by acting as a substitute to the actual metabolites that would be used in the normal metabolism (for example antifolates interfere with the use of folic acid).
Antimetabolites are drugs used in cancer chemotherapy. Cancer cells divide more rapidly compared to normal cells so antimetabolites affect cancer cell replication more than they affect normal cell replication.
See also
Medical conditions associated with antimetabolites:
- Acute Lymphoblastic Leukemia
- Acute Lymphocytic Leukemia
- Acute Myeloid Leukemia
- Acute Nonlymphocytic Leukemia
- Anemia, Sickle Cell
- Autoimmune Hepatitis
- Bladder Cancer
- Brain Tumor
- Breast Cancer
- Breast Cancer, Metastatic
- Breast Cancer, Palliative
- Bullous Pemphigoid
- Cancer
- Cervical Cancer
- Choriocarcinoma
- Chronic Lymphocytic Leukemia
- Chronic Myelogenous Leukemia
- Cogan's Syndrome
- Colorectal Cancer
- Crohn's Disease, Acute
- Crohn's Disease, Maintenance
- Dermatomyositis
- Ectopic Pregnancy
- Eczema
- Esophageal Carcinoma
- Gastric Cancer
- Graft-versus-host disease
- Hairy Cell Leukemia
- Head and Neck Cancer
- Hodgkin's Lymphoma
- Inflammatory Bowel Disease
- Intestinal Arterial Insufficiency
- Leukemia
- Liver Metastasis in Adenocarcinoma
- Lymphoma
- Malignant Pleural Mesothelioma
- Meningeal Leukemia
- Meningitis, Lymphomatous
- Multiple Sclerosis
- Mycosis Fungoides
- Myelodysplastic Syndrome
- Neoplastic Diseases
- Non-Hodgkin's Lymphoma
- Non-Small Cell Lung Cancer
- Osteosarcoma
- Ovarian Cancer
- Pancreatic Cancer
- Pemphigoid
- Pemphigus
- Peripheral T-cell Lymphoma
- Pityriasis rubra pilaris
- Polycythemia Vera
- Prostate Cancer
- Psoriasis
- Psoriatic Arthritis
- Renal Cell Carcinoma
- Rheumatoid Arthritis
- Small Cell Lung Cancer
- Soft Tissue Sarcoma
- Solid Tumors
- Stem Cell Transplant Conditioning
- Stomach Cancer
- Systemic Sclerosis
- Trophoblastic Disease
- Ulcerative Colitis, Maintenance
- Uveitis
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